{"product_id":"berberine-cofactors","title":"Berberine \u0026 Cofactors","description":"\u003cp\u003e\u003cspan\u003eComplex to support the processes of weight loss, improve metabolism, normalize glucose and cholesterol levels. It has a powerful antioxidant and anti-inflammatory effect.\u003c\/span\u003e\u003c\/p\u003e\n\u003csection class=\"im21--product-about__section\"\u003e\n\u003ch2 class=\"im21--headline-xl im21--headline-md-tablet im21--headline-sup-s-mobile\"\u003eOverview\u003c\/h2\u003e\n\u003cdiv class=\"im21--product-about__text-container ng-animation_slide\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWe lose weight quickly and safely\u003c\/strong\u003e\u003cbr\u003eHelps to lose weight and start the fat burning process by increasing insulin sensitivity and improving glucose absorption by tissue cells. Chromium and zinc accelerate metabolism, help the body use glucose more efficiently, reduce cravings for sweets, reducing total calorie intake.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWe keep sugar under control\u003c\/strong\u003e\u003cbr\u003eHelps reduce insulin resistance. This makes the product effective for people with pre-diabetes and type 2 diabetes. Provides support for the normal function of the pancreas, helps the body to use energy more efficiently. Zinc is responsible for the correct collection of insulin in the pancreas, its adequate production in the required amount.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWe take care of the vessels\u003c\/strong\u003e\u003cbr\u003eHelps to convert cholesterol into bile acids, thus contributing to its removal from the body and, accordingly, reducing its level in the blood. Provides a significant reduction in the content of triglycerides, total cholesterol and \"bad\" cholesterol (LDL) in the vessels, while increasing the level of \"good\" cholesterol (HDL), which has a beneficial effect on the cardiovascular system.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eStrike a triple blow on excess weight!\u003c\/strong\u003e\u003cbr\u003eThe fast pace of life, lack of time, stress and constant temptations in the form of fast food are a serious test for our health. Unbalanced diet and sedentary lifestyle lead to excess blood sugar and extra pounds, thus opening the way to metabolic problems. Often we don't even realize that constant snacks can negatively affect our well-being and figure. At the same time, it is sometimes simply impossible to replace a sweet or burger with something healthy.\u003cbr\u003eThe complex with berberine and zinc and chromium cofactors, thanks to the combination of assets, contributes to the normalization of carbohydrate metabolism, correction and prevention of insulin resistance, fat burning and effective weight loss.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe secret of slimness and health\u003cbr\u003eA formula that definitely works\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImproving insulin sensitivity\u003c\/strong\u003e\u003cbr\u003eBy stimulating the activity of the insulin receptor, it helps to reduce insulin resistance, as well as control blood glucose levels, suppressing the process of gluconeogenesis in the liver and blocking the action of glucagon. This effect is achieved due to the impact on the key enzymes of this process. Thus, berberine improves physiological glucose stimulation through the cascade reaction of insulin-like growth factor-1 (IGF-1), thereby causing insulin secretion in the body, reducing insulin resistance and improving the sensitivity of the liver, muscle tissue and fat to insulin. Zinc is a mineral that helps to package insulin in granules in the pancreas, thus normalizing carbohydrate metabolism.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEffective weight loss\u003c\/strong\u003e\u003cbr\u003eBerberine has the effect of combating excess body weight. It is based on the ability to inhibit adipogenesis, stimulate thermogenesis in brown adipose tissue, optimize the structure of fibrosed adipose tissue.\u003cbr\u003eStudies prove the ability of berberin to counteract the formation of fat cells and prevent obesity caused by a high-calorie diet. In addition, berberine helps the body to fully absorb carbohydrates from food, completely process them and spend them as a source of energy. In combination with chromium, the effectiveness of reducing body weight and the appetite control process increases.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlucose level control\u003c\/strong\u003e\u003cbr\u003eBerberine helps maintain normal blood glucose levels, inhibiting the process of gluconeogenesis in the liver. This effect is achieved by exposure to key enzymes of this process, such as PEPCK (phosphoenolpyruvate carboxykinase) and G6Pase (glucose-6-phosphatase). Recent studies show that barberry extract can reduce blood glucose levels by blocking the effect of glucagon. Thus, the complex with berberine helps to maintain the balance between the processes of formation and cleavage of glucose molecules.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNormalization of lipid metabolism\u003c\/strong\u003e\u003cbr\u003eHelps reduce cholesterol and triglycerides, while increasing the level of HDL. Taking berberin helps to convert cholesterol into bile acids, which helps to reduce blood cholesterol levels, as bile acids are the main way to remove cholesterol from the body. Thus, berberine affects the metabolism of lipids, as well as the regulation of intestinal microflora.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-inflammatory and antioxidant effect\u003c\/strong\u003e\u003cbr\u003eBerberine has powerful antioxidant properties, protecting cells from damage and reducing inflammatory processes, reduces the production of inflammatory mediators. The mechanisms of this effect include the impact on various signaling pathways in the immune system, which is activated in response to inflammatory stimuli.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e• \u003cstrong\u003eBarberry extract\u003c\/strong\u003e\u003cbr\u003ePromotes the regulation of energy metabolism, improves insulin sensitivity and increases fat burning, lowers blood sugar levels and normalizes cholesterol levels. It has a choleretic and antispasmodic effect, lowers the tone of the gallbladder muscles, reduces the amplitude of its contractions, promotes bile secretion. When taking berberine, there is an increase in bile secretion, a decrease in its viscosity, and normalization of the biochemical composition of bile.\u003cbr\u003e• \u003cstrong\u003eZinc citrate\u003c\/strong\u003e\u003cbr\u003eResponsible for the correct assembly of insulin granules in the pancreas and their subsequent release.\u003cbr\u003eImproves the functioning of the immune system, is part of antiviral and antibacterial complexes due to the ability to restore the body during a cold. Zinc also has a beneficial effect on skin regeneration in case of injuries and inflammation, prevents the development of acne. Moreover, this element is involved in the generation of enzymes necessary for high-quality protein synthesis and cell division. Zinc supports taste and smell receptors, has a positive effect on the cognitive functions of the brain - concentration and memory.\u003cbr\u003e• \u003cstrong\u003eChromium picolinate\u003c\/strong\u003e\u003cbr\u003eA trace element that plays an important role in regulating the metabolism of carbohydrates, fats and proteins. Improves the effect of insulin and increases receptor sensitivity to it, contributing to the stabilization of blood glucose levels. Reduces cravings for sweets. Helps maintain the normal function of the pancreas. Participates in metabolic processes, contributing to more efficient use of energy by the body.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor whom?\u003c\/strong\u003e\u003cbr\u003e∙ For those who want to reduce body weight.\u003cbr\u003e∙ For those who have insulin resistance, type 2 diabetes, metabolic syndrome.\u003cbr\u003e∙ For sweet tooth and all those who need adequate sugar support.\u003cbr\u003e∙ For those who are faced with high \"bad\" cholesterol.\u003cbr\u003e∙ For those who suffer from frequent infections.\u003cbr\u003e∙ For those who need to prevent bile excretion.\u003cbr\u003e∙ For those whose diet is oversaturated with heavy, fatty food.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e3 capsules contain:\u003c\/strong\u003e\u003cbr\u003e• \u003cstrong\u003e200 μg of chromium (from chromium picolinate)\u003c\/strong\u003e\u003cbr\u003eTo reduce cravings for sweets and normalize metabolism.\u003cbr\u003e• \u003cstrong\u003e24 mg of zinc (from zinc citrate)\u003c\/strong\u003e\u003cbr\u003eFor adequate insulin production and metabolism improvement.\u003cbr\u003e• \u003cstrong\u003e300 mg of berberine HCl (from barberry extract)\u003c\/strong\u003e\u003cbr\u003eFor effective fat burning, reducing blood sugar and cholesterol levels.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\u003csection class=\"im21--product-about__section\"\u003e\n\u003ch2 class=\"im21--headline-xl im21--headline-md-tablet im21--headline-sup-s-mobile im21--product-about__headline\"\u003eUse\u003c\/h2\u003e\n\u003cdiv class=\"im21--product-about__text-container\"\u003e\n\u003cp\u003eAdults - 1 capsule 3 times a day with meals. The duration of admission is 30 days. If necessary, the reception can be repeated.\u003c\/p\u003e\n\u003ch2 class=\"im21--headline-xl im21--headline-md-tablet im21--headline-sup-s-mobile\"\u003eContents\u003c\/h2\u003e\n\u003cdiv class=\"im21--product-composition__content\"\u003e\n\u003cp\u003eMicrocrystalline cellulose (carrier), barberry extract (fruits, fruits, shoots of Berberis sp.), zinc citrate, magnesium stearate (anti-caking agent), chromium picolinate.\u003cbr\u003eCapsule shell: beef gelatin, iron oxide (dye).\u003c\/p\u003e\n\u003cp\u003eThere may be traces of cereals containing gluten, peanuts, nuts, eggs, soy, mustard, sesame, celery, milk, fish, crustaceans, mollusks and their processed products.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e3 capsules contain:\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eActive components\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"center\"\u003e\u003cstrong\u003eWeight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"center\"\u003e\u003cstrong\u003e% of AUP*\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eChromium (from chromium picolinate)\u003c\/td\u003e\n\u003ctd align=\"center\"\u003e200 mcg\u003c\/td\u003e\n\u003ctd align=\"center\"\u003e400**\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eZinc (from zinc citrate)\u003c\/td\u003e\n\u003ctd align=\"center\"\u003e24 mg\u003c\/td\u003e\n\u003ctd align=\"center\"\u003e200**\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBerberine HCl (from barberry extract)\u003c\/td\u003e\n\u003ctd align=\"center\"\u003e300 mg\u003c\/td\u003e\n\u003ctd align=\"center\"\u003e–***\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e* AUP - adequate level of consumption according to the ESEGT.\u003cbr\u003e** Does not exceed the upper permissible level of consumption according to the ESEGT.\u003cbr\u003e*** AUP is not installed.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e","brand":"Siberian Wellness Online Store","offers":[{"title":"Default Title","offer_id":43619990306894,"sku":null,"price":47.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0263\/5451\/6046\/files\/Screenshot2026-04-10at7.29.12PM.png?v=1775874601","url":"https:\/\/siberianwellnesssd.com\/products\/berberine-cofactors","provider":"Siberian Wellness Online Store","version":"1.0","type":"link"}